Valturna is the first and only single-pill blood pressure medicine that targets two key points in the RAAS (renin-angiotensin-aldosterone system). The RAAS plays an important role in the normal rise and fall of your blood pressure.

Renin, an enzyme in the body, works at the start of the RAAS and leads to the production of angiotensin II, a potent chemical that causes blood vessels to tighten and narrow.

If the RAAS is too active within your body, your blood vessels may tighten and narrow too much and your blood pressure can become too high.

The combined medicines in Valturna allow it to target the RAAS at two different points. This is how Valturna reduces the level and effect of angiotensin II.

As a result, Valturna helps blood vessels relax and widen so blood pressure is lowered.

The combined medicines in Valturna are aliskiren and valsartan. Aliskiren is a direct renin inhibitor (DRI) that reduces the level of angiotensin II. Valsartan is an angiotensin receptor blocker (ARB) that blocks the effect of the remaining angiotensin II.